MIP-T3 Expression Associated with Defects of Ciliogenesis in Airway of COPD Patients

Figure 2

MIP-T3 expression in bronchial epithelium. Immunohistochemistry analysis of the MIP-T3 protein expression in epithelial cells and cilia of nonsmokers (a), healthy smokers (b), and COPD smokers (c), black lines represented 200 μm. The level of MIP-T3 protein and mRNA expression was determined by western blotting and real-time PCR (d,e). The correlation analysis between the MIP-T3 protein expression and the percentage of abnormal cilia was shown (f). Data were expressed as mean ± SD, value < 0.05 vs nonsmoker group, and value < 0.05 vs healthy smoker group.

(a)

(b)

(c)

(d)

(e)

(f)