Extracorporeal Shock Waves Increase Markers of Cellular Proliferation in Bronchial Epithelium and in Primary Bronchial Fibroblasts of COPD Patients

Figure 7

NF-κB-p65 mRNA (a, b, c) and protein (d, e, f) expression after ESW treatment in primary bronchial fibroblasts of COPD patients (a, d), primary bronchial fibroblasts of control smokers (b, e), and bronchial epithelial cells (c, f). In bronchial epithelium (16HBE), NF-κB-p65 increased at protein (panel f) level at 4 and 24 h of exposure. In primary bronchial fibroblasts of COPD patients, NF-κB-p65 decreased at protein level (d) at 24 h. In primary bronchial fibroblasts of control smokers, NF-κB-p65 increased at protein level ( e) at 72 h. T-test was used for comparative purposes, and values are reported in the graphs.

(a)

(b)

(c)

(d)

(e)

(f)