Survival Analysis of Risk Factors for Mortality in a Cohort of Patients with Tuberculosis

Table 2

Univariate analysis of risk factors for death during the treatment period in 7,032 tuberculosis patients.

Variable	Total N = 7,032	Death status		HR	95% CI
		Died N = 321 (N, %)	Alive N = 6,711 (N, %)		Lower	Upper
Age (years)				1.059	1.052	1.067	<0.001
Sex
Female	2,111	58 (2.7)	2,053 (97.3)	1.000
Male	4,921	263 (5.3)	4,658 (94.7)	1.968	1.481	2.615	<0.001
Ethnicity
Predominant group (Han)	6,920	313 (4.5)	6,607 (95.5)	1.000
Ethnic groups	112	8 (7.1)	104 (92.9)	1.597	0.792	3.222	0.191
Patient type
New	5,638	218 (3.9)	5,420 (96.1)	1.000
Relapse	1,394	103 (7.4)	1,291 (92.6)	1.776	1.400	2.252	<0.001
First sputum bacteria results
Negative/not tested	3,730	105 (2.8)	3,625 (97.2)	1.000
Positive	3,302	216 (6.5)	3,086 (93.5)	2.430	1.925	3.068	<0.001
Pulmonary cavity
No	5,556	248 (4.5)	5,308 (95.5)	1.000
Yes	1,476	73 (4.9)	1,403 (95.1)	1.137	0.876	1.477	0.334
HIV status
Negative/not tested	7,013	318 (4.5)	6,695 (95.5)	1.000
Positive	19	3 (15.8)	16 (84.2)	3.483	1.117	10.858	0.031
Drug resistance results
Non-drug resistance	6,130	276 (4.5)	5,854 (95.5)	1.000
Drug resistance	902	45 (5.0)	857 (95.0)	1.259	0.919	1.726	0.152
Patient delay (d)
<14	5,044	214 (4.2)	4,830 (95.8)	1.000
≥14	1,988	107 (5.4)	1,881 (94.6)	1.291	1.023	1.628	0.031
Diagnosis delay (d)
<14	2,696	121 (4.5)	2,575 (95.5)	1.000
≥14	4,336	200 (4.6)	4,136 (95.4)	1.015	0.810	1.272	0.897

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