Comparisons of Metabolic Load between Adaptive Support Ventilation and Pressure Support Ventilation in Mechanically Ventilated ICU Patients

Table 4

Comparisons of metabolic and respiratory measurements among 3 PS levels.

	PS0 cmH2O	PS8 cmH2O	PS12 cmH2O
EE (kcal)	1425 ± 76	1284 ± 6	1169 ± 58	<0.001	c < a, b; b < c
VO2 (ml/min)	218 ± 11	195 ± 9	178 ± 8	<0.001	c < a, b; b < c
VCO2 (ml/min)	143 ± 7	135 ± 7	121 ± 7	<0.001	c < a, b
MV (L/min)	9.1 ± 1	9.3 ± 1.1	8.7 ± 1	0.21
Spont RR (bpm)	21 ± 1	19 ± 1	18 ± 1	0.01	c < a, b; b < c
Vt (ml)	442 ± 25	498 ± 30	501 ± 30	<0.001	c > a, b; b > c
Ppeak (cmH2O)	12 ± 1	16 ± 1	20 ± 1	<0.001	c > a, b; b > c
MAP (cmH2O)	9.1 ± 2	10.8 ± 1	11.8 ± 1	<0.001	c > a, b; b > c
P0.1 (cmH2O)	−4.4 ± 0.4	−3.3 ± 0.4	−2.7 ± 0.3	<0.001	c < a, b; b < c

MV, minute ventilation; EE, energy expenditure; , oxygen consumption; , carbon dioxide production; Vt, tidal volume; RR, respiratory rate; MV, minute ventilation; Ppeak, peak pressure; MAP, mean airway pressure; P0.1, airway occlusion pressure; a, PS0 cmH₂O; b, PS8 cmH₂O; c, PS12 cmH₂O. Variables comparison over 3 levels of PS were analyzed by repeated-measures ANOVA, .