Canadian Respiratory Journal

Research Article

Comparisons of Metabolic Load between Adaptive Support Ventilation and Pressure Support Ventilation in Mechanically Ventilated ICU Patients

Table 5

Comparisons of metabolic and respiratory measurements among 3 ASV trials.


	ASV_PS0	ASV_PS8	ASV_PS12

EE (kcal)	1069 ± 73	1116 ± 70	1017 ± 70	<0.001	c < b
VO₂ (ml/min)	161 ± 10	169 ± 10	154 ± 10	<0.001	c < b
VCO₂ (ml/min)	116 ± 9	120 ± 8	108 ± 8	0.01	c < a, b
MV (%)	145 ± 6	144 ± 6	143 ± 6	0.82
MV (L/min)	8.9 ± 0.9	8.8 ± 1	8.6 ± 1	0.52
Spont RR (bpm)	17 ± 1	16 ± 1	16 ± 1	0.25
Vt (ml)	520 ± 23	539 ± 27	529 ± 26	0.14
Ppeak (cmH₂O)	21 ± 4	21 ± 3	21 ± 4	0.90
MAP (cmH₂O)	12 ± 1	12.2 ± 1	12 ± 1	0.74
Delta (cmH₂O)	13 ± 4.2	13.4 ± 3.8	13.3 ± 4.3	0.94
P0.1 (cmH₂O)	−2.1 ± 0.2	−2.2 ± 0.2	−1.8 ± 0.2	0.12

MV, minute ventilation; EE, energy expenditure; , oxygen consumption; , carbon dioxide production; Vt, tidal volume; RR, respiratory rate; MV, minute ventilation; Ppeak, peak pressure; MAP, mean airway pressure; P0.1, airway occlusion pressure; Delta P, difference between Ppeak and PEEP. a, PS0 cmH₂O; b, PS8 cmH₂O; c, PS12 cmH₂O. Variables comparison over 3 levels of PS were analyzed by repeated-measures ANOVA, .