Analysis of Optimal Health-Related Quality of Life Measures in Patients Waitlisted for Lung Transplantation

Table 5

Stepwise multiple regression analyses to predict the SGRQ, MRF-26 and SRI scores.

	SGRQ total	MRF-26 total	SRI summary
PaCO2	—	—	—
%FEV1	—	—	—
%FVC	0.07	0.05	—
6MWD	0.04	0.05	0.05
mMRC dyspnea	0.28	0.21	0.17
HADS anxiety	0.12	0.14	0.25
HADS depression	0.21	0.19	0.17
Cumulative R^2	0.71	0.64	0.64

All values represent coefficient of determination (R²). Missing values (—) indicate no significant relationships. SGRQ: St. George’s Respiratory Questionnaire; MRF: Maugeri Respiratory Failure Questionnaire; SRI: Severe Respiratory Insufficiency Questionnaire; PaCO₂,:partial pressure of arterial carbon dioxide; FEV₁: forced expiratory volume in one second; FVC: forced vital capacity; 6MWD: 6-minute walk distance; mMRC: modified Medical Research Council; HADS: Hospital Anxiety and Depression Scale.