Validation of the NoSAS Score for the Screening of Sleep-Disordered Breathing in a Sleep Clinic
Table 2
Predictive values of NoSAS score and STOP-Bang questionnaire at different AHI cutoffs.
Screening tools
Sensitivity (95% CI)
Specificity (95% CI)
PPV (95% CI)
NPV (95% CI)
AUC (95% CI)
AHI ≥ 5
0.330
NoSAS
71.2% (87.7–93.0)
62.4% (52.0–73.6)
92.4% (89.2–94.7)
26.0% (20.2–32.8)
0.715 (0.655–0.775)
STOP-Bang
90.7% (87.7–93.0)
30.5% (21.0–41.8)
89.1% (86.0–91.6)
34.4% (23.8–46.4)
0.693 (0.631–0.755)
AHI ≥ 10
0.072
NoSAS
76.7% (72.2–80.7)
53.7% (46.6–60.7)
86.5% (72.0–80.5)
54.0% (46.8–61.0)
0.705 (0.661–0.749)
STOP-Bang
92.9% (89.9–95.2)
22.4% (17.0–28.9)
70.2% (66.0–74.0)
61.6% (49.5–72.5)
0.672 (0.627–0.718)
AHI ≥ 15
0.046
NoSAS
80.4% (75.5–84.5)
49.3% (43.4–55.3)
64.1% (59.2–68.8)
69.0% (62.0–75.2)
0.697 (0.655–0.739)
STOP-Bang
93.7% (90.2–96.0)
18.9% (14.6–24.1)
56.6% (52.2–60.9)
72.6% (60.7–82.1)
0.663 (0.619–0.706)
AHI ≥ 20
0.165
NoSAS
81.4% (75.8–85.9)
44.1% (38.9–49.5)
50.8% (45.7–55.8)
77.0% (70.4–82.5)
0.697 (0.654–0.739)
STOP-Bang
95.1% (91.4–97.3)
17.5% (13.7–22.0)
44.9% (40.7–49.3)
83.6% (72.6–90.8)
0.671 (0.627–0.714)
AHI ≥ 25
0.264
NoSAS
82.6% (76.6–87.4)
42.2% (37.2–47.2)
43.2% (38.3–48.2)
82.0% (74.8–86.9)
0.685 (0.640–0.729)
STOP-Bang
95.2% (91.0–97.5)
16.2% (12.8–20.3)
37.7% (33.5–42.0)
86.3% (75.8–92.9)
0.664 (0.618–0.709)
AHI ≥ 30
0.512
NoSAS
83.1% (76.6–88.2)
40.7% (36.0–45.6)
37.4% (32.6–42.4)
85.0% (79.1–89.5)
0.688 (0.641–0.735)
STOP-Bang
95.5% (91.0–97.9)
15.5% (12.3–19.5)
32.5% (28.5–36.7)
89.0% (79.0–94.8)
0.675 (0.628–0.722)
value of DeLong test comparing AUCs of both screening tools. AHI: apnea-hypopnea index; PPV: positive predictive value; NPV: negative predictive value; AUC: area under the receiver operating characteristics curve.
