Research Article

Head-To-Head Comparison of Treatment Failure and Costs among COPD Patients Who Used Noninvasive Ventilation in the Ward versus in the ICU: A Propensity-Matched Cohort Study

Table 1

Clinical characteristics of the patients who used NIV in the ward versus those in the ICU.

In the ward N = 83In the ICU N = 319

Age, years71 ± 873 ± 90.10
Male/female63/20243/76>0.99
Underlying disease
 Hypotension27 (33%)110 (35%)0.80
 Diabetes mellitus16 (19%)61 (19%)>0.99
 Chronic heart disease13 (16%)63 (20%)0.44
 Chronic kidney disease0 (0%)14 (4%)0.08
 Chronic liver disease1 (1%)10 (3%)0.47
Data collected at initiation of NIV
 APACHE II score15 ± 216 ± 40.09
 GCS14.8 ± 0.714.4 ± 1.50.02
 Respiratory rate, breaths/min24 ± 328 ± 6<0.01
 Heart rate, beats/min98 ± 19108 ± 22<0.01
 Mean arterial pressure, mmHg91 ± 11100 ± 18<0.01
 pH7.29 ± 0.057.26 ± 0.06<0.01
 PaCO2, mmHg80 ± 1383 ± 170.08
 PaO2/FiO2, mmHg228 ± 70208 ± 900.05

NIV = noninvasive ventilation, ICU = intensive care unit, GCS = Glasgow coma scale, APACHE II = acute physiology and chronic health evaluation II.