High-Flow Nasal Cannula versus Noninvasive Positive Pressure Ventilation in Patients with Heart Failure after Extubation: An Observational Cohort Study
Table 2
Outcomes of patients between the HFNC and NPPV groups.
Outcomes
HFNC (n = 58)
NPPV (n = 46)
value
Primary outcome
Treatment failure within 72 hours, n
15 (25.9)
6 (13)
0.106
Type of treatment failure
Hypoxemia respiratory failure, n
11 (73.3)
1 (16.7)
0.046∗
Hypercapnia respiratory failure, n
3 (20)
2 (33.3)
0.598
Excessive effort for breathing, n
0
1 (16.7)
0.286
Cardiac arrest, n
1 (6.7)
0
>0.99
Airway protection, n
0
2 (33.3)
0.71
Time to treatment failure, hours
17 (4–54)
36 (4.5–49.8)
0.726
Secondary outcome
Reintubation within 72 hours, n
10 (17.2)
6 (13)
0.556
Hospital reintubation, n
17 (29.3)
14 (30.4)
0.901
Time to reintubation, hours
69 (14–274)
145 (40.5–221.3)
0.691
ICU length of stay, days
14 (8–21.8)
11 (8–16.3)
0.138
Hospital length of stay, days
23.5 (16–46.3)
27 (18.5–38)
0.883
ICU mortality, n
1 (1.7)
1 (2.2)
>0.99
Hospital mortality, n
3 (5.2)
8 (17.4)
0.057
Values are mean ± SD, median (Q1–Q3), or number (percentage %); ICU, intensive care unit; HFNC, high-flow nasal cannula; NPPV, noninvasive positive pressure ventilation. .
