The miR-146a SNP Rs2910164 and miR-155 SNP rs767649 Are Risk Factors for Non-Small Cell Lung Cancer in the Iranian Population

Table 5

Association of SNPs with NSCLC according to stage and subtypes.

Variable	rs2910164							rs767649
	GG	CG	CC	Allele G frequency (%)	Allele C frequency (%)	Adjusted OR (95%CI)	value	TT	TA	AA	Allele T frequency (%)	Allele A frequency (%)	Adjusted OR (95%CI)	value
Stage I (n = 4)	2	2	0	6 (0.75)	2 (0.25)			4	0	0	4 (100)	0 (0%)
Stage II (n = 18)	7	10	1	24 (0.67)	12 (0.33)	0.66 (0.11–3.81)	0.64	15	3	0	33 (0.92)	3 (0.08)	1.06 (0.04–24.1)	0.96
Stage III (n = 33)	15	15	3	45 (0.68)	21 (0.32)	0.71 (0.13–3.84)	0.69	27	6	0	60 (0.91)	6 (0.09)	1.03 (0.04–21.4)	0.98
Stage IV (n = 110)	45	54	11	144 (0.65)	76 (0.35)	0.63 (0.12–3.20)	0.57	85	19	6	189 (0.86)	31 (0.14)	0.66 (0.03–12.7)	0.78
ADC type (n = 135)	57	65	13	179 (0.66)	91 (0.34)			106	25	4	237 (0.88)	33 (0.12)
SCC type (n = 24)	11	11	2	33 (0.69)	15 (0.31)	1.11 (0.57–2.16)	0.73	20	3	1	43 (0.89)	5 (0.11)	1.19 (0.44–3.23)	0.72
LCC type (n = 6)	1	5	0	7 (0.58)	5 (0.42)	0.71 (0.21–2.30)	0.75	5	0	1	10 (0.83)	2 (0.17)	0.69 (0.14–3.31)	0.64