Smoking Status Modifies the Relationship between Th2 Biomarkers and Small Airway Obstruction in Asthma

Table 3

Association between Th2 biomarkers, smoking status, and small airway obstruction.

Variables	Unadjusted			Adjusted
	OR	95% CI	value	OR	95% CI	value
Current smoking^a	2.239	1.070–4.684	0.032	4.677	1.593–13.730	0.005
Ex-smoking^b	2.111	0.867–5.137	0.100	2.316	0.760–7.055	0.140
Lg (Eos)^c	1.560	1.057–2.303	0.025	1.520	0.948–2.437	0.082
Lg (IgE)^d	0.636	0.392–1.032	0.067	0.403	0.216–0.754	0.004

Exposure category: adjusted for sex, age, BMI, family income, education level, and asthma grade, including ^aLg (Eos), Lg (IgE); ^bLg (Eos), Lg (IgE); ^csmoking status, Lg (IgE); ^dsmoking status, Lg (Eos). Reference is never-smoking status. Lg (IgE), log10 transformed total IgE level in serum. Lg (Eos), log10 transformed eosinophil count in blood. Bold shows statistically significant value.