Smoking Status Modifies the Relationship between Th2 Biomarkers and Small Airway Obstruction in Asthma

Table 4

Association between Th2 biomarkers and small airway obstruction by smoking status.

Variables	Unadjusted			Adjusted
	OR	95% CI	value	OR	95% CI	value
Current smoking
Lg (Eos)^a	1.929	0.564–6.603	0.295	0.473	0.062–3.616	0.471
Lg (IgE)^b	0.558	0.131–2.386	0.432	0.113	0.009–1.358	0.086
Ex-smoking
Lg (Eos)^a	1.275	0.302–5.386	0.741	1.422	0.259–7.791	0.685
Lg (IgE)^b	0.266	0.028–2.562	0.252	0.065	0.002–2.706	0.151
Never smoking
Lg (Eos)^a	1.588	1.029–2.452	0.037	1.612	0.953–2.725	0.075
Lg (IgE)^b	0.683	0.399–1.168	0.164	0.487	0.249–0.954	0.036

Exposure category: adjusted for sex, age, BMI, family income, education level, and asthma grade, including ^aLg (IgE); ^bLg (Eos). Lg (IgE), log10 transformed total IgE level in serum. Lg (Eos), log10 transformed eosinophil count in blood. Bold shows statistically significant value.