LASP1 Induces Epithelial-Mesenchymal Transition in Lung Cancer through the TGF-<i>β</i>1/Smad/Snail Pathway

<div>(a–d) LASP1 knockdown and overexpression efficiency in TGF-<i>β</i>1-treated A549 and SK-MES-1 cells. After coinfection with 2 ng/ml TGF-<i>β</i>1 and lentivirus containing LASP1 shRNA or 2 ng/ml TGF-<i>β</i>1 and pcDNA-LASP1, the cells were lysated to detect mRNA and protein levels of LASP1. Fold change mRNA expression levels of LASP1 were quantified by RT-qPCR in A549 (a) and SK-MES-1 (c) cells. Western blot confirmed the change of LASP1 protein levels in A549 (b) and SK-MES-1 (d) cells. 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Canadian Respiratory Journal

fig2

Figure 2

Figure 2: LASP1 Induces Epithelial-Mesenchymal Transition in Lung Cancer through the TGF-<i>β</i>1/Smad/Snail Pathway 

Canadian Respiratory Journal

LASP1 Induces Epithelial-Mesenchymal Transition in Lung Cancer through the TGF-β1/Smad/Snail Pathway

Figure 2