Efficacy and Safety of Ergoferon in Children from 6 Months to 6 Years Old with Acute Respiratory Viral Infections in Contemporary Outpatient Practice: A Multicenter, Double-Blind, Placebo-Controlled Randomized Trial
Table 2
Results of multiplex real-time RT-PCR assays of patients.
Type of virus
Group
Statistics
Ergoferon (n = 140), abs (%)
Placebo (n = 142), abs (%)
hRV
28 (20)
29 (20.4)
IAV
9 (6.4)
6 (4.2)
hMPV
5 (3.6)
8 (5.6)
hPIV types 1, 2, 3, 4
5 (3.6)
7 (4.9)
hCoV types OC43, 229E, HKU1, NL63
6 (4.3)
1 (0.7)
hBoV
4 (2.9)
1 (0.7)
hAV B, C, E
3 (2.1)
2 (1.4)
IBV
3 (2.1)
5 (3.5)
hRSV
1 (0.7)
0 (0)
IAV + IAV H1N1pdm
3 (2.1)
2 (1.4)
IBV + hAV B, C, E
6 (4.3)
5 (3.5)
hRSV + hRV
2 (1.4)
1 (0.7)
hRSV + hCoV
0 (0)
1 (0.7)
hRSV + hMPV
0 (0)
1 (0.7)
hAV B, C, E + hRV
1 (0.7)
0 (0)
hAV B, C, E + hBoV
0 (0)
1 (0.7)
hBoV + hRV
1 (0.7)
0 (0)
hPIV + hRV
1 (0.7)
3 (2.1)
hPIV types 1, 2, 3, 4 + hAV types B, C, E + hRV
0 (0)
1 (0.7)
hMPV + hBoV
1 (0.7)
0 (0)
hMPV + hRV
1 (0.7)
3 (2.1)
hMPV + hRV + hBoV
0 (0)
1 (0.7)
No virus found
60 (42.9)
64 (45.1)
Statistics, CMH
Value = 0.018;
hRV: human rhinovirus; IAV: influenza A virus; hMPV: human metapneumovirus; hPIV: human parainfluenza virus; hCoV: human coronaviruses; hBoV: human bocavirus; hAV: human adenovirus; IBV: influenza B virus; hRSV: human respiratory syncytial virus; IAV H1N1pdm: influenza A (H1N1) pdm virus. Fisher's exact test. CMH: Cochrane–Mantel–Haenszel test. CMH test applicability was accessed using Breslow–day test ().
