Research Article

Characteristics and Clinical Course of Adult Inpatients with SARS-CoV-2 Pneumonia at High Altitude

Table 1

Characteristics on admission to hospital and outcomes of the study population.

Total (n = 377)Survivor (n = 292)Nonsurvivor (n = 85)

Age, years59.7 ± 16.456.7 ± 15.870.1 ± 13.9
<50103 (27.3)97 (33.2)6 (7.1)
50–65130 (34.5)108 (37.0)22 (25.9)
>65144 (38.2)87 (29.8)57 (67.1)

Sex
Female163 (43.2)135 (46.2)28 (32.9)
Male214 (56.8)157 (53.8)57 (67.1)

Symptoms
Cough335/360 (93.1)262/281 (93.2)73/79 (92.4)
Fever280/346 (80.9)219/272 (80.5)61/74 (82.4)
Dyspnea258/294 (87.8)191/222 (86.0)67/72 (93.1)
Asthenia136/137 (99.3)117/118 (99.2)19/19 (100.0)
Sore throat106/153 (69.3)91/128 (71.1)15/25 (60.0)
Diarrhea77/154 (50.0)63/121 (52.1)14/33 (42.4)

Comorbidities
Arterial hypertension149 (39.5)99 (33.9)50 (58.8)
Overweight145 (38.5)122 (58.2)23 (27.1)
Obesity114 (30.2)90 (30.8)24 (28.2)
Diabetes mellitus82 (21.8)55 (18.8)27 (31.8)
Chronic obstructive pulmonary disease34 (9.0)17 (5.8)17 (20.0)
Chronic kidney disease19 (5.0)10 (3.4)9 (10.6)
Coronary artery disease18 (4.8)13 (4.5)5 (5.9)
Heart failure17 (4.5)10 (3.4)7 (8.2)

Number of comorbidities
044 (11.7)32 (11.0)12 (14.1)
1169 (44.8)130 (44.5)39 (45.9)
283 (22.0)63 (21.6)20 (23.5)
357 (15.1)48 (16.4)9 (10.6)
≥424 (6.4)19 (6.5)5 (5.9)

Smoking status
Current smoking7 (1.9)6 (2.1)1 (1.2)
Former smoking38 (10.1)28 (9.6)10 (11.8)
Body mass index27.3 (24.1–30.9)27.4 (24.8–31.0)25.8 (22.8–30.9)

Baseline vital signs
Systolic blood pressure, mmHg128.0 (116.0–140.0)127.0 (115.0–138.0)130.0 (119.3–151.8)
Heart rate, bpm96.3 ± 17.596.0 ± 16.597.1 ± 20.7
Respiratory rate, bpm20 (18–22)20 (18–21)20 (19–24)

Pneumonia severity

CURB-65
0 or 1251/342 (73.4)215/262 (82.1)36/80 (45.0)
279/342 (23.1)41/262 (15.6)38/80 (47.5)
≥312/342 (3.5)6/262 (2.3)6/80 (7.5)

qSOFA
0 or 1324/337 (96.3)267/275 (97.1)75/80 (93.8)
≥213/337 (3.7)8/275 (2.9)5/80 (6.2)
Days from illness onset to hospital admission7 (4–9)7 (4–10)6 (4–8)
Days from illness onset to ICU admission9 (6–11)9 (7–12)8 (6–10)

Outcomes
Invasive mechanical ventilation123 (32.6)50 (17.1)73 (85.9)
ICU admission158 (41.9)85 (29.1)73 (85.9)
ICU length of stay, days8 (3–15)7 (3–14)10 (3–17)
Length of hospital stay, days9 (6–15)9 (6–14)10 (5–18)

Data are presented as mean ± standard deviation, median (interquartile range), or n/N (%), where N is the total number of patients with available data.