Research Article

Characteristics and Clinical Course of Adult Inpatients with SARS-CoV-2 Pneumonia at High Altitude

Table 2

Laboratory and radiographic findings of the study population on admission to hospital.

Total (n = 377)Survivor (n = 292)Nonsurvivor (n = 85)

Laboratory findings
White blood cell count, ×109/L7.545 (5.510–10.035)7.140 (5.380–9.540)8.550 (6.235–12.075)
<424/376 (6.4)21/291 (7.2)3/85 (3.5)
4 to 10257/376 (68.4)205/291 (70.4)52/85 (61.2)
>1095/376 (25.3)65/291 (22.3)30/85 (35.3)
Lymphocyte count, ×109/L1.105 (0.803–1.468)1.150 (0.890–1.520)0.810 (0.560–1.250)
<1156/376 (41.5)102/291 (35.1)54/85 (63.5)
≥1220/376 (58.5)189/291 (64.9)31/85 (36.5)
Hemoglobin, mg/dL14.8 ± 2.014.9 ± 1.814.5 ± 2.6
<12.538/376 (10.1)20/291 (6.9)18/85 (21.2)
≥12.5338/376 (89.9)271/291 (93.1)67/85 (78.8)
Platelet count, ×109/L218.000 (177.000–274.750)225.000 (179.000–281.000)196.000 (159.000–251.500)
<1009/376 (2.4)7/291 (2.4)2/85 (2.4)
≥100367/376 (97.6)284/291 (97.6)83/85 (97.6)
Lactate dehydrogenase, U/L344.0 (266.5–462.0)325.0 (258.0–414.5)458.0 (310.0–646.0)
≤25070/365 (19.2)63/282 (22.3)7/83 (8.4)
>250295/365 (80.8)219/282 (77.7)76/83 (91.6)
Ferritin, ng/mL854.0 (472.0–1500.0)768.5 (470.8–1406.5)1131.0 (512.5–1942.5)
<600112/315 (35.6)90/238 (37.8)22/77 (28.6)
≥600203/315 (64.4)148/238 (62.2)55/77 (71.4)
C-reactive protein, mg/L112.3 (63.6–181.7)101.3 (55.1–167.2)143.8 (99.1–226.1)
<5058/309 (18.8)52/241 (21.6)6/68 (8.8)
≥50251/309 (81.2)189/241 (78.4)62/68 (91.2)
Procalcitonin, ng/mL0.27 (0.11–0.93)0.18 (0.09–0.59)0.73 (0.25–1.84)
<0.115/70 (21.4)14/48 (29.2)1/22 (4.5)
0.1 to <0.528/70 (40.0)20/48 (41.6)8/22 (36.4)
≥0.527/70 (38.6)14/48 (29.2)13/22 (59.1)
D-dimer, mg/L0.49 (0.28–0.93)0.46 (0.27–0.90)0.65 (0.37–1.14)
<0.5184/364 (50.6)156/283 (55.1)28/81 (34.6)
0.5 to 1.0101/364 (27.7)71/283 (25.1)30/81 (37.0)
>1.079/364 (21.7)56/283 (19.8)23/81 (28.4)
Creatinine, mg/dL0.97 (0.79–1.21)0.90 (0.76–1.12)1.19 (0.96–1.58)
<1.5314/363 (86.5)254/278 (91.4)60/85 (70.6)
≥1.549/363 (13.5)24/278 (8.6)25/85 (29.4)
Alanine aminotransferase, U/L35.0 (22.0–58.5)38.0 (22.8–61.0)30.5 (18.3–51.8)
≤40181/314 (57.6)128/234 (54.7)53/80 (66.3)
>40133/314 (42.4)106/234 (45.3)27/80 (33.7)
Arterial pH7.44 (7.42–7.46)7.44 (7.42–7.47)7.43 (7.4–7.46)
<7.4037/370 (10.0)19/286 (6.6)18/84 (21.4)
7.40–7.47277/370 (74.9)221/286 (77.3)56/84 (66.7)
>7.4756/370 (15.1)46/286 (16.1)10/84 (11.9)
SpO2, %90.5 (86.9–93.9)91.0 (87.0–94.0)90.0 (84.2–92.8)
<90161/370 (38.4)121/286 (42.3)40/84 (47.6)
≥90209/370 (61.6)165/286 (57.7)44/84 (52.4)
PaO2/FiO2 ratio239.0 (198.0–270.0)246.5 (213.8–274.0)188.5 (152.5–239.8)
<10018/370 (4.9)5/286 (1.7)13/84 (15.5)
100 to 19977/370 (20.8)44/286 (15.4)33/84 (39.3)
200 to 299236/370 (63.8)204/286 (71.3)32/84 (38.1)
≥30039/370 (10.5)33/286 (11.5)6/84 (7.1)
Viral coinfection4/63 (6.3)3/34 (8.8)1/29 (3.4)
Bacterial coinfection10/109 (9.2)5/65 (7.7)5/44 (11.4)

Chest X-ray features
Normal63/354 (17.8)56/271 (20.7)7/83 (8.4)
Compatible with pneumonia257/354 (72.6)187/271 (69.0)70/83 (84.3)
Compatible with an alternative diagnosis10/354 (2.8)8/271 (2.9)2/83 (2.4)
Nonspecific features24/354 (6.8)20/271 (7.4)4/83 (4.8)

Chest CT features
Compatible with viral pneumonia323/344 (93.9)261/274 (95.3)62/70 (88.6)
Compatible with an alternative diagnosis15/344 (4.4)11/274 (4.0)4/70 (5.7)
Nonspecific features6/344 (1.7)2/274 (0.7)4/70 (5.7)
Pulmonary embolism on CT pulmonary angiography6/66 (1.6)6/57 (2.1)0/9 (0.0)

Data are presented as mean ± standard deviation, median (interquartile range), or n/N (%), where N is the total number of patients with available data.