Role of Toll-Like Receptor 2 in Regulation of T-Helper Immune Response in Chronic Obstructive Pulmonary Disease
Table 1
Clinical characteristics of the examined groups.
Characteristics
Control group
COPD GOLD I
COPD GOLD II
COPD GOLD III
Total number
97
107
132
84
Sex (male/female)
56/41
63/44
74/58
49/35
Age (years)
51.3 ± 2.5
55.9 ± 2.5
56.8 ± 4.2
61.3 ± 2.4
Smoking status (smokers/ex-smokers)
0
85/22
94/38
59/25
Smoking index (pack/year)
0
24.3 ± 6.5
27.3 ± 5.2
29.4 ± 5.9
Postbronchodilator FEV1 (% of the normal)
104.7 ± 2.0
90.2 ± 3.1
72.6 ± 2.4
41.5 ± 2.8
Postbronchodilator FEV1 (% predicted)
80.75 ± 3.1
61.3 ± 2.4
55.9 ± 1.8
43.7 ± 2.0
mMRC test (score)
0
1.0 ± 0.6
1.45 ± 0.3
1.73 ± 0.8
CAT (score)
0
4.3 ± 1.0
8.5 ± 0.9
12.6 ± 0.1
Number of exacerbations per year
0
0
0.9 ± 0.2
1.9 ± 0.5
Notes. Data are presented as mean ± standard deviation. Statistical significance of differences in comparison with the control group (Student's t-test): .
