Role of Toll-Like Receptor 2 in Regulation of T-Helper Immune Response in Chronic Obstructive Pulmonary Disease

Table 2

The percentage of CD4⁺CD282⁺ cells in the peripheral blood of healthy individuals and patients with COPD of varying severity with Th1 and Th17 cytokine profiles.

Control group	COPD GOLD I, n = 107		COPD GOLD II, n = 132		COPD GOLD III, n = 84
	Th1 cytokine profile, n = 72	Th17 cytokine profile, n = 35	Th1 cytokine profile, n = 62	Th17 cytokine profile, n = 70	Th1 cytokine profile, n = 21	Th17 cytokine profile, n = 63
1.1 (0.8–1.3)	1.22 (0.96–1.42)	1.57 (1.11–1.72)	1.85 (1.64–2.06)	2.65 (2.48–2.89)	2.11 (1.92–2.27)	3.94 (3.41–4.3)

Notes. Data are presented as median, upper, and lower quartiles. Statistical significance of the differences between the groups of COPD patients and the control group (Mann–Whitney U test): and . Statistical significance of the differences between the groups of patients with COPD of the same severity but with different Th cytokine profiles (Mann–Whitney U test): and .