Role of Toll-Like Receptor 2 in Regulation of T-Helper Immune Response in Chronic Obstructive Pulmonary Disease

Table 3

Correlations between the percentage of CD4⁺CD282⁺ cells in the peripheral blood, serum levels of Th cytokines, and clinical parameters in patients with COPD of varying severity.

Parameters	COPD GOLD I	COPD GOLD II	COPD GOLD III
	CD4^+CD282^+ (%)
IL-6 (pg/mL)	0.71	0.69	0.87
IL-10 (pg/mL)	−0.63	0.53	—
IL-17A (pg/mL)	0.77	0.67	0.96
IL-21 (pg/mL)	0.79	0.85	0.94
Postbronchodilator FEV1 (% predicted)	−0.68
Postbronchodilator FEV1/FVC (%)	−0.87

Notes. Data are presented as Spearman’s correlation coefficient (r). Statistical significance (Mann–Whitney U test): .