Development and Relevance of Hypercapnia in COPD

Table 2

Multiple regression analysis assessing hypercapnia.

	OR	value
FEV1 pp	0.98 (0.97–0.99)	<0·01
Presence of emphysema	0.72 (0.50–1.05)	0·09
Use of LTOT	1.74 (1.19–2.53)	<0·01
DLCOpp	0.92 (0.89–0.94)	<0.01
FRCpp	1.17 (1.09–1.25)	<0.01

The ORs shown represent the effect of increasing FEV₁ by 1% of predicted, and DLCO, by 1% predicted, having emphysema not, using LTOT not, increasing age by 1 year, and current smoking not. p = percent predicted.