The Extent of Honeycombing on Computed Tomography Cannot Predict the Treatment Outcome of Patients with Acute Exacerbations of Interstitial Lung Disease
Table 4
Univariate and multivariate analysis of primary predictors of 3-month mortality.
Variable
Univariates
Multivariates
Odds ratio
95% CI
Odds ratio
95% CI
Honeycomb present
Age
1.067
0.912–1.087
0.918
Sex
5.348
0.629–45.479
0.125
CCIS
1.494
0.970–1.652
0.082
Diagnosis of ILDs
0.589
0.124–2.797
0.505
Serum LDH
1.005
1.002–1.008
0.005
1.005
1.002–1.007
<0.001
Serum KL-6
1.000
1.000–1.001
0.454
P/F ratio
0.998
0.990–1.006
0.580
GGO score
0.886
0.723–1.085
0.244
Honeycomb absent
Age
1.066
0.953–1.216
0.270
Sex
4.174
0.183–95.180
0.340
CCIS
1.494
1.098–2.311
0.009
1.436
1.156–1.842
0.001
Diagnosis of ILDs
3.389E + 10
0
1.000
Serum LDH
1.004
0.994–1.015
0.996
Serum KL-6
1.000
0.999–1.001
0.906
P/F ratio
1.004
0.982–1.006
0.425
GGO score
1.060
0.897–1.247
0.482
CCIS, Charlson Comorbidity Index Score; CI, confident interval; GGO, ground-glass opacity; ILD, interstitial lung disease; LDH, lactate dehydrogenase; KL-6, Krebs von den Lungen; P/F ratio, partial pressure of oxygen in arterial blood/fraction of inspired oxygen.