Research Article
Nomogram for Predicting the Relationship between the Extent of Visceral Pleural Invasion and Survival in Non-Small-Cell Lung Cancer
Table 2
Univariate and multivariate Cox regression analysis of the training group.
| Variable | Univariate analysis | Multivariate analysis | -value | HR (95% CI) | -value |
| Sex | <0.001 | | | Female | Reference | | Male | 1.370 (1.332–1.410) | <0.001 |
| Age(years) | <0.001 | | | <60 | Reference | | ≥60 | 1.374 (1.324–1.427) | <0.001 |
| Race | <0.001 | | | Black | Reference | | White | 1.039 (0.997–1.084) | 0.0708 | Other | 0.820 (0.767–0.877) | <0.001 |
| Marital Status | <0.001 | | | Married | Reference | | Divorced | 1.203 (1.153–1.255) | <0.001 | Single | 1.172 (1.124–1.223) | <0.001 | Widowed | 1.371 (1.320–1.424) | <0.001 | Unknown | 1.084 (1.008–1.165) | 0.0287 |
| Histology | <0.001 | | | AC | Reference | | BAC | 0.702 (0.649–0.759) | <0.001 | LCC | 1.388 (1.262–1.528) | <0.001 | SC | 1.193 (1.158–1.228) | <0.001 |
| Grade | <0.001 | | | I | Reference | | II | 1.204 (1.141–1.271) | <0.001 | III | 1.467 (1.390–1.547) | <0.001 | IV | 1.453 (1.293–1.634) | <0.001 |
| T stage | <0.001 | | | T1 | Reference | | T2 | 1.395 (1.339–1.454) | <0.001 | T3 | 1.642 (1.571–1.717) | <0.001 | T4 | 1.745 (1.667–1.826) | <0.001 |
| N stage | <0.001 | | | N0 | Reference | | N1 | 1.278 (1.228–1.330) | <0.001 | N2 | 1.515 (1.472–1.559) | <0.001 | N3 | 1.453 (1.395–1.514) | <0.001 |
| M stage | <0.001 | | | M0 | | Reference | | M1 | | 2.427 (2.361–2.494) | <0.001 |
| Pleural | <0.001 | | | PLX | | Reference | | | | 0.499 (0.484–0.515) | <0.001 | | | 0.465 (0.430–0.503) | <0.001 | | | 0.478 (0.441–0.519) | <0.001 | | | 0.605 (0.546–0.670) | <0.001 |
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