Impact of HACOR Score on Noninvasive Ventilation Failure in Non-COPD Patients with Acute-on-Chronic Respiratory Failure
Table 2
Vital signs and ventilator parameters from initiation to 24 h of NIV for patients who experienced successful NIV and NIV failure.
Successful NIV
NIV failure
Before NIV
Heart rate (bpm)
107 ± 22
122 ± 23
<0.01
Respiratory rate (bpm)
29 ± 6
28 ± 5
0.68
Mean arterial blood pressure (mmHg)
101 ± 16
103 ± 22
0.76
GCS score
14.5 ± 1.2
14.2 ± 1.2
0.38
pH
7.26 ± 0.07
7.22 ± 0.07
0.01
PaCO2 (mmHg)
81 ± 18
77 ± 17
0.28
PaO2/FiO2, (mmHg)
199 ± 99
173 ± 79
0.28
1-2 h of NIV
Heart rate (bpm)
96 ± 18
111 ± 26
<0.01
Respiratory rate (bpm)
23 ± 5
25 ± 6
0.07
Mean arterial blood pressure (mmHg)
91 ± 13
103 ± 19
<0.01
GCS score
14.7 ± 0.7
13.7 ± 1.3
<0.01
pH
7.35 ± 0.05
7.26 ± 0.10
<0.01
PaCO2 (mmHg)
68 ± 18
74 ± 22
0.25
PaO2/FiO2 (mmHg)
223 ± 63
169 ± 70
<0.01
Support pressure (cmH2O)
17 ± 4
17 ± 4
0.58
PEEP (cmH2O)
6 ± 2
6 ± 2
0.47
12 h of NIV
Heart rate (bpm)
89 ± 16
113 ± 31
<0.01
Respiratory rate (bpm)
22 ± 4
22 ± 3
0.85
Mean arterial blood pressure (mmHg)
88 ± 11
91 ± 14
0.48
GCS score
14.8 ± 0.5
14.5 ± 0.7
0.02
pH
7.38 ± 0.05
7.27 ± 0.12
<0.01
PaCO2 (mmHg)
65 ± 15
71 ± 22
0.19
PaO2/FiO2 (mmHg)
241 ± 86
182 ± 64
0.03
Support pressure (cmH2O)
18 ± 4
18 ± 3
0.89
PEEP (cmH2O)
7 ± 3
6 ± 2
0.53
24 h of NIV
Heart rate (bpm)
87 ± 17
105 ± 30
<0.01
Respiratory rate (bpm)
23 ± 4
25 ± 6
0.11
Mean arterial blood pressure (mmHg)
90 ± 12
92 ± 23
0.61
GCS score
14.9 ± 0.9
14.2 ± 0.8
0.02
pH
7.40 ± 0.07
7.29 ± 0.14
<0.01
PaCO2 (mmHg)
59 ± 15
73 ± 33
0.01
PaO2/FiO2 (mmHg)
256 ± 80
171 ± 68
<0.01
Support pressure (cmH2O)
19 ± 4
20 ± 3
0.78
PEEP (cmH2O)
7 ± 3
6 ± 2
0.32
NIV, noninvasive ventilation; GCS, Glasgow Coma Scale; PEEP, positive end-expiratory pressure. Differences between the two groups were analyzed with independent samples t tests.
