Research Article
Identification of Signal Pathways and Hub Genes of Pulmonary Arterial Hypertension by Bioinformatic Analysis
| | Hub gene | Description | Degree |
| | HSP90AA1 | Heat shock protein 90 alpha family class a member 1 | 121 | | CDC5L | Cell division cycle 5 like | 114 | | MDM2 | MDM2 proto-oncogene | 94 | | LRRK2 | Leucine rich repeat kinase 2 | 88 | | CFTR | Cystic fibrosis transmembrane conductance regulator | 60 | | IQGAP1 | IQ motif containing GTPase activating protein 1 | 59 | | CAND1 | Cullin associated and neddylation dissociated 1 | 48 | | TOP2A | DNA topoisomerase II alpha | 48 | | DDX21 | DExD-box helicase 21 | 46 | | HIF1A | Hypoxia inducible factor 1 subunit alpha | 45 |
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