Research Article

Feasibility of Using High-Resolution Computed Tomography Features for Invasiveness Differentiation of Malignant Nodules Manifesting as Ground-Glass Nodules

Table 1

Patient demographic information comparison between the training and testing cohorts and semantic imaging feature comparison between the invasiveness subtypes and differentiation ability in terms of AUC.

Patient demographical information

TrainingTesting value

Age54.9 (±10.80)55.6 (±10.89)0.69
Gender0.24
 Female155 (70.1%)43 (78.2%)
 Male66 (29.9%)12 (21.8%)

GGO characteristic
Training valueAUCTesting valueAUC

Pre-MIAInvasive-Pre-MIAInvasive-
Nodule type<0.00010.670.00090.67
Pure102 (98.08%)75 (64.1%)26 (100%)19 (65.52%)
Part-solid2 (1.92%)42 (35.90%)0 (0%)10 (34.48%)
Lesion margin0.020.78<0.00010.75
Smooth74182412
Lobular or spiculated3099217
Air bronchial sign present3 (2.88%)8 (6.84%)0.182 (7.69%)4 (13.79%)0.67
Pleural indentationpresent2 (1.92%)51(43.52%)<0.00010.711(3.85%)11 (37.93%)0.00270.67
Vascular convergence present1 (0.96%)32 (27.35%)<0.00010(0%)4 (13.79%)0.11
DGGN10.01 (±4.65)15.38 (±7.22)<0.0118.11 (±8.80)9.32 (±2.45)<0.0001
GGN<10 mm6211153
GGN>10 mm421061126

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