Prognostic Role of Chronic Obstructive Pulmonary Disease and Asthma Physiology Score for in-Hospital and 1-year Mortality in Patients with Acute Exacerbations of COPD

Table 3

Baseline characteristics stratified by CAPS.

Characteristic	CAPS ≥21 points (67)	CAPS <21 points (173)	P Value
Hospitalization mortality (%)	23.88	1.16	<0.001
Age (years)	81.18 ± 6.79	75.71 ± 8.21	<0.001
Sex, n (%)			0.544
Male	51 (76.1)	125 (72.3)
Female	16 (23.9)	48 (27.7)
BMI (kg/m^2)	20.92 ± 3.95	21.51 ± 3.81	0.288
Hospital stay (days)	8.09 ± 3.18	7.55 ± 2.81	0.204
Smoking status, n (%)			0.135
Never smoked	12 (17.9)	47 (27.2)
Current smoker/ever smoked	55 (82.1)	126 (72.8)
Smoking history (pack-years)	41.37 ± 37.68	35.21 ± 33.69	0.220
COPD stage, n (%)			0.228
I	3 (4.5)	17 (9.8)
II	32 (47.8)	61 (35.3)
III	21 (31.3)	67 (38.7)
IV	11 (16.4)	28 (16.2)
CHF, n (%)	22 (32.8)	21 (12.1)	<0.001
RD, n (%)	20 (29.9)	7 (4.0)	<0.001
Exacerbations during preceding year, n (%)	39 (58.2)	79 (45.7)	0.081
Number of acute exacerbations before admission (times)	1.0 (0, 2.0)	0 (0, 1.0)	0.047
Lymphocyte count (×10^9/L)	1.07 ± 0.91	1.42 ± 0.65	0.001
Percentage of neutrophils (%)	82.3 ± 11.6	73.4 ± 11.1	<0.001
PH	7.39 ± 0.09	7.39 ± 0.04	0.642
PaO2 (mmHg)	88.3 ± 27.2	90.3 ± 26.0	0.592
PaCO2 (mmHg)	44.0 ± 13.2	45.7 ± 11.2	0.339

CAPS, chronic obstructive pulmonary disease and asthma physiology score; CHF, congestive heart failure; RD, renal dysfunction.