Review Article

Inspiratory Muscle Rehabilitation Training in Pediatrics: What Is the Evidence?

Table 3

Inspiratory muscle rehabilitation training (IMRT) in youth athletes.

CitationStudy DesignPopulationInterventionOutcomesLimitations

Wells et al. 2005 [24]RCTNational-level competitive swimmers, 15.6 ± 1.3 years n = 34 (20 females, 14 males)Duration: 12 weeksAt 6 weeks, no change in MIP and MEP in IMRT or sham groups; at 12 weeks, ∆MIP = 14.4 cmH20 and ∆MEP = 20 cmH20 in females (combining IMRT and sham subjects) with no changes in malesNo statistical between-group comparisons reported
Frequency: 10 sessions/weekMVV15, FEV1, and FVC increased in both IMRT and sham groups after 12 weeks; no difference between IMRT and sham at 6 weeks
Intensity: 50% weeks 1–3 and 60% weeks 3–6 for MIP and MEP; 70% weeks 7–9 and 80% weeks 10–12 for MIP and MEPNo differences in performance (swim velocity) or dyspnea
Volume: 10 breaths per session
Type: inspiratory and expiratory flow-resistive loading
Equipment: PowerLung
Control: sham IMRT (10% MIP and MEP) for 6 weeks followed by moderate IMRT (50% weeks 7–9 and 60% weeks 10–12 for MIP and MEP)
(Both groups continued regular swim training; only first 6 weeks represent differences between IMRT and sham)

Kilding et al. 2010 [25]RCTClub-level competitive swimmers n = 16 (6 females, 10 males)Duration: 6 weeks∆MIP = 10.5 cmH20 in IMRT group vs. 0.3 cmH20 in sham group
Frequency: 7 days/weekSwim time improved for 100 m and 200 m time trials, but not for 400 m time trial
Intensity: 50% MIP. Instructed to increased load periodically so that 30 breaths could only just be completedRating of perceived exertion decreased across a range of intensities
Volume: 30 breaths, twice a dayFVC, FEV1, PEF: No change
Type: pressure threshold loadingMEP not reported
Equipment: POWER-breathe
Control: sham IMRT, 60 slow protracted breaths once daily at 15% MIP

Lemaitre et al. 2013 [26]Controlled before and after studySwimmers, 13–18 yr, avg. training 45–48 wk/yr, 20 h/wk n = 20 (7 females, 13 males)Duration: 8 weeks∆MIP = ≈25 cmH20 in RMET group vs. no change in control groupMIP and MEP reported in figures (absolute values not reported)
Frequency: 5 days per week∆MEP = ≈25 cmH20 in RMET group vs. no change in control group
Intensity: 60% of MVV12Competition swim time on 50 m and 200 m improved
Volume: 30 minRespiratory endurance test breathing duration increased from 16 to 24.6 min
Type: voluntary isocapnic hyperpnea (respiratory muscle endurance training or RMET)VEmax and maximum breathing frequency increased
Equipment: SpiroTigerRating of perceived exertion and rating of perceived dyspnea reduced
Control: usual training onlyduring the 50 m and 200 m race
FVC (% pred) and MVV increased

Lomax et al. 2019 [27]RCTSwimmers, two groups based on training distance (low and high) n = 33 (15 females, 18 males)Duration: 6 weeks∆MIP = ≈55 cmH20 (high-training IMRT group), ≈35 cmH20 (low-training IMRT group) and ≈20 cmH20 (high-training control group)MIP reported in figures (pre and post absolute values not reported). 36% improvement in MIP (combined for high and low-training IMRT groups) reported in text of article
Frequency: 7 days/wkNo change in MEP
Intensity: 50% MIP. Instructed to increased load periodically so that 30 breaths could only just be completed100 m and 200 m swimming times improved in the low-training IMRT group only
Volume: 30 breaths, twice a day
Type: pressure threshold loading
Equipment: POWER-breathe
Control: usual swim training only

Okrzymowska et al. 2019 [29]RCTDisabled swimming division athletes, 16–20 yr n = 16 (8 females, 8 males)Duration: 8 weeks∆MIP = 33 cmH20 (IMRT group) and 16 cmH20 (control group)
Frequency: 5 days/weekFVC, FEV1, and PEF increased in IMRT group
Intensity: 30% MIP in week 1, increased to 40% in weeks 2 and 3, 50% in weeks 4 and 5, and 60% in weeks 6–8MEP increased in both groups
Volume: 30 breaths, 5 min in week 1 increased to 15 min in week 8, twice a day
Type: pressure threshold loading
Equipment: philips respironics
Control: usual swim training only

Vašíčková et al. 2017 [28]Randomized controlled trial (parallel arm with control group receiving the IMRT intervention after a 1-month washout)Club-level fin-swimmers n = 20 (did not report sample size by sex)Duration: 4 weeksMIP increased by 20.8% in the IMRT group vs. 1.5% in the control group (post 4 weeks)Results reported as median values; absolute values not reported for MIP and MEP
Frequency: 7 days/weekMEP increased by 10.6% in the IMRT group vs. 5.1% decrease in the control group (post 4 weeks)
Intensity: 30% MIP and MEP and increased by 2 cm H20 every week until maximum possible resistance on the threshold devicesLength able to swim for one inspiration increased by 27.4% (IMRT in first phase), 20.7% (IMRT in second phase)
Volume: 10 maximal inspirations and 10 maximal expirations (strength) + 15 min of continuous breathing against resistance (endurance)FVC, FEV1, PEF: no change
Type: pressure threshold loading (inspiratory and expiratory)
Equipment: philips respironics
Control: usual swim training (with IMRT completed in second phase after washout)

Mackala et al. 2019 [30]RCTClub-level competitive junior soccer players n = 16 malesDuration: 8 weeks∆MIP = 44 cmH20 (IMRT group) vs. 11 cmH20 (control group)
Frequency: 5 days/week∆MEP = 41 cmH20 (IMRT group) vs. 4 cmH20 (control group)
Intensity: 40% MIP in week 1, increased by 5% every week to 80% in week 8Running test distance increased by 5% in IMRT group vs. 2.1% in the control group (both changes were statistically significant)
Volume: 5 repetitions in week 1 to 15 repetitions in week 8, each repetition was 45 s of IMRT followed by a 15 s break, twice a dayFVC improved in IMRT group
Type: pressure threshold loadingFEV1 improved in both groups
Equipment: philips respironics
Control: usual training only

Note. RCT–randomized control trial, MIP–maximal inspiratory pressure, MEP–maximal expiratory pressure, MVV12–Maximal voluntary ventilation measured by assessing ventilation during maximal voluntary effort for 12 seconds and extrapolating to calculate maximal ventilation in liters per minute, FEV1–forced expiratory volume in 1 second, FVC–forced vital capacity, PEF–peak expiratory flow, and VEmax–maximal ventilation.