Comparison of CRP, Procalcitonin, Neutrophil Counts, Eosinophil Counts, sTREM-1, and OPN between Pneumonic and Nonpneumonic Exacerbations in COPD Patients

Table 5

Logistic regression model of factors predicting CAP in AECOPD.

Variables	OR (95% CI)	Value
Purulent sputum	—	0.08
Increased sputum volume	—	0.19
Diabetes mellitus	—	0.06
SCS treatment	—	0.22
FEV1, % predicted	—	0.35
CRP ≥ 15.8 mg/dL	10.72 (4.76–24.13)	<0.001
Neu ≥ 6.41 × 10^9/L	—	0.16
PCT ≥ 0.07 ng/mL	—	0.10
OPN ≥ 13.26 ng/mL	—	0.26

Variables, including sputum purulence, increased sputum volume, diabetes mellitus, SCS treatment, FEV1, % predicted, PCT ≥ 0.07 ng/mL, Neu ≥ 6.41 × 10^9/L, CRP ≥ 15.8 mg/dL, and OPN ≥ 13.26 ng/mL, were retained as covariates in the forward stepwise selection procedure of multivariate analysis.