Research Article

Two-Photon Laser Scanning Microscopy of the Transverse-Axial Tubule System in Ventricular Cardiomyocytes from Failing and Non-Failing Human Hearts

Figure 3

Geometrical Dimensions of Human Ventricular Myocytes from Failing and Non-Failing Hearts. Cell length and width were measured from transmitted light images of each cell taken with a 60× lens at 1- to 2-fold zoom (a,b). Cell length-width ratio was calculated from these data (c). Sarcomere length was measured from 6–9 sarcomeres in the transmitted light images (d). Open bars show the dimensions for myocytes from non-failing hearts (11 cells, 2 hearts), closed bars represent cells from failing human hearts (37 cells, 4 hearts). Calculated p-values as given, stars symbolize statistical significance.
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(a)
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(b)
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(c)
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(d)