Impact of Moderate to Severe Renal Impairment on Mortality and Appropriate Shocks in Patients with Implantable Cardioverter Defibrillators

Table 2

Hazard ratios with 95% confidence intervals for time to first appropriate shock based on GFR.

	Unadjusted	Adjusted*
GFR (mL/min/1.73 m^2)
≥60	ref	ref
30–59 (moderate CKD)	1.15 (0.84–1.58)	1.15 (0.83–1.58)
<30 (severe CKD)	1.92 (1.09–3.38)	2.42 (1.35–4.34)

*Adjusted for age (≥75 or <75 years), sex, indication for ICD implantation (primary/secondary), NYHA class, heart failure admission, antiarrhythmic/betablocker use, and LVEF (<30%, ≥30%).