ST-Segment Depression in Hyperventilation Indicates a False Positive Exercise Test in Patients with Mitral Valve Prolapse

Table 2

Exercise and electrocardiographic parameters.

	Males (𝑛=103)	Females (𝑛=115)	𝑃 value
Exercise parameters
Exercise duration (sec)	520±32	470±25	0.036
Resting systolic blood pressure (mmHg)	134±12	136±13	NS
Systolic blood pressure at hyperventilation (mmHg)	142±11	144±12	NS
Maximal systolic blood pressure (mmHg)	188±16	193±15	NS
Resting heart rate (bpm)	80±5	78±4	NS
Heart rate at hyperventilation (bpm)	106±6	106±5	NS
Maximal heart rate (bpm)	162±9	169±6	NS
Exercise-induced Angina	8/103 (8%)	6/115 (5%)	NS
Electrocardiographic parameters
Presence of ↓ ST at hyperventilation:	27/103 (26%)	41/115 (36%)	.041
(i) inferior leads (II, III, aVF)	12/103 (12%)	19/115 (17%)	.045
(ii) anterior leads (V1, V2, V3)	0/103 (0%)	2/115 (2%)	.038
(iii) lateral leads (V4, V5, V6)	5/103 (5%)	7/115 (6%)	NS
(iv) inferior + lateral leads (II, III, aVF, V4, V5, V6)	10/103 (10%)	13/115 (11%)	NS
Maximal ↓ ST at hyperventilation (mV):	0.09±0.03	0.11±0.05	NS
(i) inferior leads (II, III, aVF)	0.09±0.04	0.11±0.05	NS
(ii) anterior leads (V1, V2, V3)	0.02±0.02	0.01±0.01	NS
(iii) lateral leads (V4, V5, V6)	0.09±0.03	0.1±0.01	NS
Maximal ↓ ST at peak exercise (mV):	0.15±0.02	0.19±0.03	NS
(i) inferior leads (II, III, aVF)	0.15±0.05	0.19±0.03	NS
(ii) anterior leads (V1, V2, V3)	0.04±0.03	0.01±0.01	NS
(ii) lateral leads (V4, V5, V6)	0.11±0.02	0.18±0.01	.041
Time for exercise-induced ↓ ST:0.1 mV (sec)	390±16	362±12	.043

NS: Not Significant.