Research Article

Adjustment and Characterization of an Original Model of Chronic Ischemic Heart Failure in Pig

Table 1

Morphometric and functional analysis at basal time and during the follow-up. LVTDD: Left Ventricle TeleDiastolic Dimension. LVTDV: Left Ventricle TeleDiastolic Volume, dIVSW: diastolic InterVentricular Septal Wall, dPLVW: diastolic Posterior Left Ventricle Wall, E/Ea: Peak mitral inflow velocity—E- and Early diastolic—Ea-peak myocardial velocities with Tissue Doppler Imaging, LAV: Left Atrial Volume, WMS ant: Anterior Wall Motion Score, WMS inf: Inferior Wall Motion Score, and WMS Sept: Septal Wall Motion Score. Data are in mean ± SD. *P , **P compared to basal time.

Basal Time1 month2 months

LVTDD (mm)33.75 ± 3.347.25 ± 3.12*55.33 ± 5.93**
LVTDV (mL)48.81 ± 10.46106.5 ± 16.6*154.67 ± 35.47**
dIVSW (mm)7.73 ± 0.247.81 ± 1.28.67 ± 0.24*
dPLVW (mm)6.09 ± 0.217.38 ± 0.9*7.53 ± 0.47*
E/Ea4 ± 0.37 ± 0.32*9 ± 0.56*
LAV (cm2)7.5 ± 2.0612.30 ± 2.48*16.84 ± 3.5**
WMS ant1 ± 0.73 ± 0.5*3 ± 0.5*
WMS inf1 ± 0.42.5 ± 0.6*3 ± 0.5*
WMS Sept122