Additive Value of B-Type Natriuretic Peptide on Rest ²⁰¹Tl-Dipyridamole Stress ^99mTc-Sestamibi Gated Myocardial SPECT in Patients with Normal Left Ventricular Systolic Function

Table 2

Correlation of logarithmically transformed BNP with clinical variables and parameters of echocardiography and SPECT.

(a) Overall patients (𝑛=224).

	r	𝑃
Clinical
Age	0.367	<.001***
Creatinine clearance	−0.226	.001**
BMI	−0.010	.883
Echocardiography
E wave	0.005	.95
A wave	0.194	.008**
Deceleration time	0.019	.801
LA size	0.089	.226
LVEF	0.019	.80
E/A ratio	−0.182	.014*
SPECT
LVEF	−0.028	.681
LVESV	0.074	.271
LVEDV	0.064	.35
Summed rest score	0.249	<.001***
Summed stress score	0.179	.008**
Summed difference score	0.106	.12

(b) Patients with true positive SPECT (𝑛=142).

	r	𝑃
Clinical
Age	0.393	<.001***
Creatinine clearance	−0.274	.001**
BMI	−0.018	.831
Echocardiography
E wave	0.045	.65
A wave	0.339	<.001***
Deceleration time	0.032	.741
LA size	0.108	.249
LVEF	0.043	.649
E/A ratio	−0.183	.052
SPECT
LVEF	−0.042	.619
LVESV	0.076	.372
LVEDV	0.099	.244
Summed rest score	0.309	<.001***
Summed stress score	0.233	.006**
Summed difference score	0.172	.043*

* 𝑃<.05; **𝑃<.01; ***𝑃<.001.
BMI: Body mass index E: mitral peak early diastolic velocity; A: mitral peak late diastolic velocity; LVEF: left ventricular ejection fraction; LVEDV: left ventricular end-diastolic volume; LVESV: left ventricular end-systolic volume.