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Cardiology Research and Practice
Volume 2011, Article ID 256347, 6 pages
Review Article

Cryoballoon Catheter Ablation in Atrial Fibrillation

Cardiac Arrhythmia Service, Heart Center, Massachusetts General Hospital, Boston, MA 02114, USA

Received 16 December 2010; Revised 5 March 2011; Accepted 25 April 2011

Academic Editor: Atul Verma

Copyright © 2011 Cevher Ozcan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Pulmonary vein isolation with catheter ablation is an effective treatment in patients with symptomatic atrial fibrillation refractory or intolerant to antiarrhythmic medications. The cryoballoon catheter was recently approved for this procedure. In this paper, the basics of cryothermal energy ablation are reviewed including its ability of creating homogenous lesion formation, minimal destruction to surrounding vasculature, preserved tissue integrity, and lower risk of thrombus formation. Also summarized here are the publications describing the clinical experience with the cryoballoon catheter ablation in both paroxysmal and persistent atrial fibrillation, its safety and efficacy, and discussions on the technical aspect of the cryoballoon ablation procedure.