Impact of Cardiac Computed Tomographic Angiography Findings on Planning of Cancer Therapy in Patients with Concomitant Structural Heart Disease
Figure 1
48-year-old female with history of childhood lymphoma treated with mediastinal radiation therapy and anthracycline chemotherapy at age 12, presented with fatigue and decreased left ventricular ejection fraction by echocardiogram. Coronary CT angiography shows nonobstructive coronary plaques and supports the diagnosis of chemotherapy-induced cardiomyopathy. (a) Curved reformat view of the right coronary artery (RCA) shows nonocclusive calcific ostial plaque (arrowheads) calcific plaque in the aortic root. The first acute marginal branch is identified (arrow). Also noted are misregistration artifacts. (b, c) Curved reformat views of the left anterior descending (LAD) (b) and circumflex (c) coronary arteries show calcific plaque (white arrowhead) in the aortic root at the origin of the left main coronary artery. The first diagonal artery (black arrowhead) is identified on the LAD view (b). The LAD origin (black arrow) and distal circumflex artery continuation (white arrow) are identified on the circumflex view (c). No significant narrowing is seen in any of the major coronary arteries. LA = left atrium. LV = left ventricle. RA = right atrium. RV = right ventricle. Ao = Aortic root. * = breast prosthesis.
