Acute Experimental Hyperthyroidism Does Not Affect Basal and Volume-Induced Atrial Natriuretic Peptide Secretion in Healthy Subjects

Table 1

Clinical and laboratory characteristics of the study population before and after T₃ administration.

Parameter	Before T3	After T3	P value
Heart rate, beats/min	72±7	75±6	.061
Mean blood pressure, mmHg	117±13	117±10	.966
T3, nmol/L	1.80±0.6	4.3±1.0	<.001
T4, nmol/L	107±18	97±20	.018
TSH, μU/mL	1.04±0.70	0.09±0.04	<.001
ANP, pmol/L	10.4±2.9	11.8±4.9	.256
PRA, nmol/L/h	1.8±1.23	2.2±0.9	.099
ALDO, pmol/L	633±472	665±325	.836

ALDO: plasma aldosterone; ANP: plasma atrial natriuretic peptide; PRA, plasma renin activity.