Research Article
The Association of the Metabolic Syndrome with PAI-1 and t-PA Levels
Table 2
PAI-1 antigen levels (ng/mL) for the association of the metabolic syndrome and other covariates.
| | Median (IQR) | Univariate models | Multivariable model |
| Age at baseline | | <0.001 | <0.001 | <40 yrs | 51 (32, 89) | 40–60 yrs | 72 (42, 123) | >60 yrs | 80 (47, 138) |
| Gender | | <0.001 | <0.001 | Male | 75 (46, 132) | Female | 59 (34, 107) |
| BMI | | <0.001 | <0.001 | <25 kg/m2 (%) | 49 (31, 79) | 25–30 kg/m2 (%) | 80 (49, 143) | >30 kg/m2 (%) | 115 (71, 189) |
| Smoking status | | <0.001 | <0.001 | Current/former | 70 (43, 126) | Nonsmokers | 64 (37, 114) |
| C-reactive protein | | <0.001 | 0.633 | ≥3.0 mg/L | 84 (45, 152) | <3.0 mg/L | 63 (38, 109) |
| Urinary albumin excretion | | <0.001 | 0.303 | <30 mg/24 h (%) | 66 (39, 116) | | | 30–300 mg/24 h (%) | 80 (48, 154) | | | >300 mg/24 h (%) | 104 (68, 134) | | |
| Insulin levels | | <0.001 | <0.001 | <8 μU/mL (%) | 52 (34, 82) | 8–12 μU/mL (%) | 77 (44, 128) | >12 μU/mL (%) | 114 (71, 181) |
| Metabolic syndrome | | <0.001 | <0.001 | Present | 126 (81, 194) | Absent | 59 (36, 103) |
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PAI-1 levels were missing in 29 (1.2%) of subjects.
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