The Association of the Metabolic Syndrome with PAI-1 and t-PA Levels

Table 3

t-PA antigen levels (ng/mL) for the association of the metabolic syndrome and other covariates.

	Median (IQR)	Univariate models	Multivariable model
Age at baseline		<0.001	<0.001
<40 yrs	2.7 (1.9, 3.5)
40–60 yrs	3.1 (2.3, 4.4)
>60 yrs	3.7 (2.7, 5.7)
Gender		<0.001	<0.001
Male	3.3 (2.4, 4.9)
Female	2.8 (2.1, 4.0)
BMI		<0.001	0.153
<25 kg/m^2 (%)	2.7 (2.1, 3.7)
25–30 kg/m^2 (%)	3.4 (2.4, 5.1)
>30 kg/m^2 (%)	3.6 (2.6, 4.9)
Smoking status		0.042	0.391
Current/former	3.0 (2.2, 4.4)
Nonsmokers	3.1 (2.3, 4.5)
C-reactive protein		0.001	0.418
≥3.0 mg/L	3.3 (2.3, 4.9)
<3.0 mg/L	3.0 (2.2, 4.3)
Urinary albumin excretion		0.10	0.383
<30 mg/24 h (%)	3.0 (2.2, 4.4)
30–300 mg/24 h (%)	3.3 (2.4, 5.0)
>300 mg/24 h (%)	4.6 (4.2, 6.3)
Insulin levels		<0.001	<0.001
<8 μU/mL (%)	2.8 (2.1, 3.8)
8–12 μU/mL (%)	3.2 (2.3, 4.7)
>12 μU/mL (%)	3.6 (2.6, 5.7)
Metabolic syndrome		<0.001	0.002
Present	3.9 (2.8, 6.0)
Absent	2.9 (2.2, 4.2)

t-PA levels were missing in 26 (1.0%) of subjects.