Dyssynchrony Assessment with Tissue Doppler Imaging and Regional Volumetric Analysis by 3D Echocardiography Do Not Predict Long-Term Response to Cardiac Resynchronization Therapy

Table 4

Assessment of QRS duration and echocardiographic dyssynchrony parameters validated in other trials to predict long-term clinical and echocardiographic response.

Pre-CRT dyssynchrony; parameters	Total; (𝑛=33)	Clinical responders; (𝑛=24)	P-value	Echocardiographic responders; (𝑛=19)	P-value
QRS (ms)
<150	9	6	0.6	6	0.7
≥150	24	18		13
TDI septal-lateral delay (ms)
<65	20	17	0.1	13	0.2
≥65	13	8		6
TDI (Tf-Ts) 12 LV segments (ms)
<32	6	5	0.5	4	0.6
≥32	27	19		15
TDI (Tf-Ts) 6 basal LV segments (ms)
<83	10	7	0.8	7	0.5
≥83	23	17		12

CRT: cardiac resynchronization therapy, LV: left ventricle, TDI: tissue Doppler imaging, Tf-Ts: difference in time to peak systolic velocity between the fastest and slowest LV segments.