Cardiology Research and Practice / 2012 / Article / Tab 4 / Clinical Study
The Experience of a Multidisciplinary Clinic in the Management of Early-Stage Breast Cancer Patients Receiving Trastuzumab Therapy: An Observational Study Table 4 Treatment outcomes.
Early stage breast cancer patients Chemotherapy Chemotherapy completion (i) Complete 45 (93.7%) (ii) Discontinued (non cardiotoxicity) 1 (2.1%) (iii) Discontinued (Patient choice) 2 (4.2%) Chemotherapy cycle delays (i) Cardiotoxicity 1 (2.1%) (ii) Completion post delays 1 (100%) Trastuzumab Trastuzumab completion (i) Complete 37 (77.1%) (ii) Discontinued (cardiotoxicity) 7 (14.6%) (iii) Discontinued (non cardiotoxicity) 2 (4.2%) (iv) Discontinued (Patient choice) 2 (4.2%) ≥90% trastuzumab completion (16–18 cycles) 39 (81.3%) Trastuzumab cycle delays (i) Cardiotoxicity 16 (33.3%) (ii) Completion post delays 12 (75%) Cardiac medication 12 (25%) (i) ACE inhibitor 10 (83.3%) (ii) Beta blocker 6 (50%) (iii) Other cardiac drugs 2 (16.7%)