Novel Neurovascular Protective Agents: Effects of INV-155, INV-157, INV-159, and INV-161 versus Lipoic Acid and Captopril in a Rat Stroke Model
Figure 1
(a) Representative photomicrographs of TTC stained, 1 mm thick coronal slices illustrating the extent of the infarct within the prefrontal cortex following 30 minutes pretreatment (i.v.) with either saline or captopril (5.0 mg/kg) and ischemia/reperfusion (I/R). (b) Effect of pretreatment with either saline or captopril on infarct volume (mm3) calculated from TTC-stained 1 mm thick coronal sections throughout the extent of the infarct following I/R and pretreatment (i.v.; 30 minutes) with either saline or captopril. Each bar represents the mean ± S.E.M (–7/group).
