Novel Neurovascular Protective Agents: Effects of INV-155, INV-157, INV-159, and INV-161 versus Lipoic Acid and Captopril in a Rat Stroke Model

Figure 4

(a) Effect of pretreatment with either 2% sodium bicarbonate (vehicle), INV-159, or INV-161 (b) on infarct volume (mm³) calculated from TTC-stained 1 mm thick coronal sections throughout the extent of the infarct following I/R. Each bar represents the mean ± S.E.M. and *indicates significance (𝑃≤0.05) from the vehicle control group (𝑛=4-5/group).

(a)

(b)