Table 1: Study codes.

ConditionICD-9 codesCPT codes

Patient identification
 Atrial fibrillation427.31
 Valvular conditionsProcedure codes:
35.0, 35.00–35.04, 35.1, 35.10–35.14, 35.2, 35.20–35.28, 35.96
33400, 33401, 33403, 33405, 33406, 33410–33415, 33417, 33420, 33422, 33425–33427, 33430, 33460, 33463–33465, 33468, 33470, 33472, 33474–33476, 33478, 33496, 33600, 33602
Outcomes
 Ischemic stroke433.x1, 434.x1, 436, 437.1, 437.9
 Major bleeding
  Intracranial hemorrhage430, 431, 432
  Other major bleeds423.0, 455.2, 455.5, 455.8, 456.0, 456.2, 459.0, 530.7, 530.8, 531.0, 531.2, 531.4, 531.6, 532.0, 532.2, 532.4, 532.6, 533.0, 533.2, 533.4, 533.6, 534.0, 534.2, 534.4, 534.6, 562.0, 562.1, 569.3, 569.85, 578, 599.7, 626.2, 626.6, 719.1, 784.7, 786.3, 852, 853
CHA2DS2-VASc components
 Cardiac failure398.91, 402.x1, 404.x3, 425, 428
 Hypertension1362.11, 401, 402, 403, 404, 405
 Diabetes mellitus1250, 357.2, 362.0, 366.41
 Prior TIA2362.34, 435
 Vascular disease410, 411, 412, 413, 414, 440, 441, 442, 443, 444, 445
Procedure codes:
00.66, 36.0, 36.1, 39.25
33510–33545, 34051, 34151, 34201, 34203, 34800–34834, 34900, 35081–35103, 35131, 35132, 35141, 35142, 35151, 35152, 35331, 35341, 35351, 35355, 35361, 35363, 35371, 35372, 35381, 35450, 35452, 35454, 35456, 35459, 35470, 35471, 35472, 35473, 35474, 35480, 35481, 35482, 35483, 35485, 35490, 35491, 35492, 35493, 35495, 35521, 35531, 35533, 35541, 35546, 35546, 35548, 35549, 35551, 35556, 35558, 35563, 35565, 35566, 35571, 35583, 35585, 35587, 35621, 35623, 35646, 35647, 35651, 35654, 35656, 35661, 35663, 35665, 35666, 35671, 92980, 92981, 92982, 92984
HAS-BLED components
 Hypertension1362.11, 401, 402, 403, 404, 405
 Abnormal renal function582, 583, 585, 586
 Abnormal liver function570, 571, 572, 573, 790.4
 Prior TIA2362.34, 435
 Excessive alcohol use291.0, 291.1, 291.2, 303, 305.0, 535.3, V11.3

Note: With the exception of valvular conditions, ICD-9 codes reported as 3 digits will include all 4-digit and 5-digit codes beginning with the same 3 digits. For 4-digit codes, any 5-digit code beginning with the same 4 digits will also be included. ICD-9 codes reported are diagnosis codes unless otherwise indicated.
1Patient must have at least 2 diagnoses documented in the same calendar quarter to be considered as having the condition.
2Risk score definition includes prior stroke, but with the exclusion of patients with prior stroke, only prior TIA is applicable in this study.