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Cardiology Research and Practice
Volume 2012, Article ID 914071, 6 pages
http://dx.doi.org/10.1155/2012/914071
Clinical Study

Cardiac Resynchronization Therapy Reduces Metaboreflex Contribution to the Ventilatory Response in Heart Failure Population

Division of Clinical Cardiology, Hôpital Cardiologique, Hôpital du Haut Lévêque, CHU Hôpitaux de Bordeaux, avenue Magellan, 33600 Pessac, France

Received 21 December 2011; Accepted 9 January 2012

Academic Editor: Mariantonietta Cicoira

Copyright © 2012 Jérémie Jaussaud et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. R. Arena, J. Myers, J. Abella et al., “Development of a ventilatory classification system in patients with heart failure,” Circulation, vol. 115, no. 18, pp. 2410–2417, 2007. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  2. K. K. Witte and A. L. Clark, “Why does chronic heart failure cause breathlessness and fatigue?” Progress in Cardiovascular Diseases, vol. 49, no. 5, pp. 366–384, 2007. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  3. M. Piepoli, A. L. Clark, M. Volterrani, S. Adamopoulos, P. Sleight, and A. J. S. Coats, “Contribution of muscle afferents to the hemodynamic, autonomic, and ventilatory responses to exercise in patients with chronic heart failure: effects of physical training,” Circulation, vol. 93, no. 5, pp. 940–952, 1996. View at Google Scholar · View at Scopus
  4. M. Schaufelberger, B. O. Eriksson, G. Grimby, P. Held, and K. Swedberg, “Skeletal muscle alterations in patients with chronic heart failure,” European Heart Journal, vol. 18, no. 6, pp. 971–980, 1997. View at Google Scholar · View at Scopus
  5. D. M. Mancini, E. Coyle, A. Coggan et al., “Contribution of intrinsic skeletal muscle changes to 31P NMR skeletal muscle metabolic abnormalities in patients with chronic heart failure,” Circulation, vol. 80, no. 5, pp. 1338–1346, 1989. View at Google Scholar · View at Scopus
  6. A. C. Scott, R. Wensel, C. H. Davos et al., “Chemical mediators of the muscle ergoreflex in chronic heart failure: a putative role for prostaglandins in reflex ventilatory control,” Circulation, vol. 106, no. 2, pp. 214–220, 2002. View at Publisher · View at Google Scholar · View at Scopus
  7. A. C. Scott, R. Wensel, C. H. Davos et al., “Skeletal muscle reflex in heart failure patients: role of hydrogen,” Circulation, vol. 107, no. 2, pp. 300–306, 2003. View at Publisher · View at Google Scholar · View at Scopus
  8. J. Jaussaud, P. Blanc, P. Bordachar, R. Roudaut, and H. Douard, “Response to cardiac resynchronization therapy: the muscular metabolic pathway,” Cardiology Research and Practice, vol. 2011, Article ID 830279, 5 pages, 2011. View at Publisher · View at Google Scholar · View at PubMed
  9. A. Auricchio, M. Kloss, S. I. Trautmann, S. Rodner, and H. Klein, “Exercise performance following cardiac resynchronization therapy in patients with heart failure and ventricular conduction delay,” American Journal of Cardiology, vol. 89, no. 2, pp. 198–203, 2002. View at Publisher · View at Google Scholar · View at Scopus
  10. J. Jaussaud, P. Blanc, N. Derval et al., “Ventilatory response and peak circulatory power: new functional markers of response after cardiac resynchronization therapy,” Archives of Cardiovascular Diseases, vol. 103, no. 3, pp. 184–191, 2010. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  11. R. Arena, J. Myers, S. S. Aslam, E. B. Varughese, and M. A. Peberdy, “Technical considerations related to the minute ventilation/carbon dioxide output slope in patients with heart failure,” Chest, vol. 124, no. 2, pp. 720–727, 2003. View at Publisher · View at Google Scholar · View at Scopus
  12. A. Cohen-Solal, J. Y. Tabet, D. Logeart, P. Bourgoin, M. Tokmakova, and M. Dahan, “A non-invasively determined surrogate of cardiac power ('circulatory power') at peak exercise is a powerful prognostic factor in chronic heart failure,” European Heart Journal, vol. 23, no. 10, pp. 806–814, 2002. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  13. A. C. Scott, D. P. Francis, L. Ceri Davies, P. Ponikowski, A. J. S. Coats, and M. F. Piepoli, “Contribution of skeletal muscle “ergoreceptors” in the human leg to respiratory control in chronic heart failure,” Journal of Physiology, vol. 529, no. 3, pp. 863–870, 2000. View at Publisher · View at Google Scholar · View at Scopus
  14. H. Schmidt, D. P. Francis, M. Rauchhaus, K. Werdan, and M. F. Piepoli, “Chemo- and ergoreflexes in health, disease and ageing,” International Journal of Cardiology, vol. 98, no. 3, pp. 369–378, 2005. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  15. S. H. Kubo, T. S. Rector, A. J. Bank, R. E. Williams, and S. M. Heifetz, “Endothelium-dependent vasodilation is attenuated in patients with heart failure,” Circulation, vol. 84, no. 4, pp. 1589–1596, 1991. View at Google Scholar · View at Scopus
  16. B. D. Duscha, W. E. Kraus, S. J. Keteyian et al., “Capillary density of skeletal muscle: a contributing mechanism for exercise intolerance in class II-III chronic heart failure independent of other peripheral alterations,” Journal of the American College of Cardiology, vol. 33, no. 7, pp. 1956–1963, 1999. View at Publisher · View at Google Scholar · View at Scopus
  17. M. F. Piepoli, A. Kaczmarek, D. P. Francis et al., “Reduced peripheral skeletal muscle mass and abnormal reflex physiology in chronic heart failure,” Circulation, vol. 114, no. 2, pp. 126–134, 2006. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  18. N. Francis, A. Cohen-Solal, and D. Logeart, “Peripheral muscle ergoreceptors and ventilatory response during exercise recovery in heart failure,” American Journal of Physiology, vol. 276, no. 3, pp. H913–H917, 1999. View at Google Scholar · View at Scopus
  19. M. Guazzi, S. Belletti, G. Tumminello, C. Fiorentini, and M. D. Guazzi, “Exercise hyperventilation, dyspnea sensation, and ergoreflex activation in lone atrial fibrillation,” American Journal of Physiology, vol. 287, no. 6, pp. H2899–H2905, 2004. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  20. A. Erol-Yilmaz, B. Atasever, K. Mathura et al., “Cardiac resynchronization improves microcirculation,” Journal of Cardiac Failure, vol. 13, no. 2, pp. 95–99, 2007. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  21. U. Corrà, A. Mezzani, P. Giannuzzi, and L. Tavazzi, “Chronic heart failure-related myopathy and exercise training: a developing therapy for heart failure symptoms,” Current Problems in Cardiology, vol. 28, no. 9, pp. 521–547, 2003. View at Google Scholar
  22. A. Y. Patwala, P. R. Woods, L. Sharp, D. F. Goldspink, L. B. Tan, and D. J. Wright, “Maximizing patient benefit from cardiac resynchronization therapy with the addition of structured exercise training: a randomized controlled study,” Journal of the American College of Cardiology, vol. 53, no. 25, pp. 2332–2339, 2009. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus