Plasma Fatty Acid Binding Protein 4 and Risk of Sudden Cardiac Death in Older Adults
Table 1
Baseline characteristics of the 4,560 participants according to tertiles of FABP4.
Tertiles of FABP4 (ng/mL)
T1 (low)
T2
T3 (high)
1,520
1,520
1,520
Mean ± SD
Range
5.8–24.9
25.0–36.4
36.5–250.0
Characteristics
value
Age (years)
0.29
BMI (kg/m2)
<0.001
Waist circumference (cm)
<0.001
Male (%)
70.1
37.7
17.9
<0.001
African American (%)
13.8
16.3
20.2
<0.001
Physical activity (kcal/week)†
1155 490–2283
810 270–1907
613 140–1500
<0.001
Smoking (%)
Never
37.3
46.6
52.1
<0.001
Former
51.3
43.8
39.1
Current
11.4
9.6
8.9
Alcohol consumption (%)
None
46.5
54.2
63.8
<0.001
≤7 drinks per week
38.4
35.4
30.1
>7 drinks per week
15.1
10.4
6.1
Health status (%)
Poor
8.5
6.9
4.4
<0.001
Fair
36.0
31.0
26.2
Good
38.8
43.1
42.7
Very good
15.1
17.2
23.2
Excellent
1.6
1.7
3.4
Less than high school (%)
75.4
74.0
70.0
0.001
Unintentional weight loss (%)
4.9
4.1
6.5
0.05
GFR-cystatin C (mL/min/1.73 m2)
<0.001
hsCRP (mg/L)†
1.8 0.87–4.1
2.6 1.3–5.4
4.2 1.9–8.8
<0.001
Prevalent coronary disease (%)
21.9
20.1
22.7
0.60
Prevalent heart failure (%)
4.0
5.0
8.9
<0.001
Estrogen use—women (%)
19.6
15.1
10.2
0.01
Hypertension medication (%)
40.4
48.8
63.2
<0.001
Systolic BP
<0.001
Diastolic BP
0.02
Total cholesterol (mg/dL)
<0.001
Lipid lowering medication (%)
5.5
8.5
8.5
0.002
Hypercholesterolemia (%)
41.6
56.1
59.7
<0.001
Data are presented as mean ± SD or percentage, unless specified otherwise; hsCRP: high-sensitive C-reactive protein; GFR: glomerular filtration rate based on cystatin C. Median (interquartile range).
