Clinical Study

Heart Rate Variability in Children with Tricyclic Antidepressant Intoxication

Table 2

Twenty-four-hour time-domain (non-spectral) and 5-minute spectral analysis results by study group.

TCA intoxication
( )
Control
( )

Mean heart rate (per minute) 148
(66–224)
78
(55–102)
<0.05
SDNN (ms)104
(94–117)
146
(134–170)
0.000
SDANN (ms)27
(25–44)
31
(26–39)
RMSDD (ms)46
(41–64)
65
(57–102)
0.049
SDNN index60
(51–70)
81
(72–96)
0.002
pNN50 (%)11.3
(8.9–20.9)
24.6
(20.8–33.4)
0.005

Frequency-domain (spectral) analysis

VLF (ms2)772
(271–3873)
806
(698–1046)
nLF (nu)27
(24–35)
17
(11–24)
0.012
nHF (nu)6.9
(5.4–8.7)
12.1
(10.7–22)
0.001
LF/HF4.6
(1.1–14.4)
0.96
(0.8–2)
0.001

Values are given as median (95% CI).