Cardiology Research and Practice / 2013 / Article / Tab 3

Clinical Study

Vitamin D Predicts All-Cause and Cardiac Mortality in Females with Suspected Acute Coronary Syndrome: A Comparison with Brain Natriuretic Peptide and High-Sensitivity C-Reactive Protein

Table 3

Hazard ratios for 25(OH)D, BNP, and hsCRP in univariate and multivariate analyses in both gender.

FemalesMales
Univariate HR (95% CI)*Multivariate HR (95% CI)*Univariate HR (95% CI)*Multivariate HR (95% CI)*

25(OH)D
  All-cause mortality0.13 (0.06–0.32)0.16 (0.06–0.42)0.45 (0.26–0.79)0.70 (0.36–1.34)
  Cardiac death0.04 (0.01–0.31)0.08 (0.01–0.59)0.30 (0.13–0.66)0.38 (0.14–1.06)
  Sudden cardiac death0.06 (0.01–0.46)0.15 (0.02–1.20)0.20 (0.07–0.60)0.29 (0.08–1.03)
BNP
  All-cause mortality9.02 (3.84–21.19)4.58 (1.56–13.45)2.86 (1.60–5.09)1.79 (0.91–3.54)
  Cardiac death12.77 (2.99–54.48)2.64 (0.57–12.18)6.04 (2.33–15.68)4.22 (1.42–12.58)
  Sudden cardiac death 7.22 (1.62–32.31)1.90 (0.31–11.73)5.87 (1.71–20.16)4.55 (1.01–20.44)
hsCRP
  All-cause mortality2.43 (1.31–4.48)1.60 (0.80–3.17)2.30 (1.31–4.03)2.10 (1.12–3.94)
  Cardiac death1.97 (0.83–4.71)0.83 (1.02–1.11)1.32 (0.65–2.69)1.08 (0.47–2.48)
  Sudden cardiac death 3.07 (0.98–9.65)1.13 (0.32–4.06)1.62 (0.66–3.95)1.40 (0.52–3.81)

25(OH)D: 25-hydroxyvitamin D; BNP: B-type natriuretic peptide; hsCRP: high-sensitivity C-reactive protein; HR: hazard ratio; CI: confidence interval.
*Highest quartile (Q4) versus lowest quartile (Q1). 25(OH)D, BNP, and hsCRP levels are highest in Q4.

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