Cardiology Research and Practice / 2014 / Article / Tab 4

Clinical Study

High-Sensitivity Troponin T: A Biomarker for Diuretic Response in Decompensated Heart Failure Patients

Table 4

Associations with at day 1, day 3 and changes between day 1 and day 3 (Δ).

Nonadjusted coefficient for 95%CI valueAdjusted coefficient for 95%CI Value

Age0,119−0,001 to 0,0050,240
Male sex−0,066−0,086 to 0,0430,515
DM0,095−0,033 to 0,0930,349
HgBA1c0,058−0,046 to 0,0670,707
LVEF0,089−0,001 to 0,0040,376
Ischemic HF−0,078−0,087 to 0,0380,442
Beta-blocker−0,004−0,065 to 0,0620,969
ACEi0,023−0,057 to 0,0720,820
Spironolactone−0,116−0,099 to 0,0260,251
BMI
 Day 1−0,205−0,025 to 0,0000,042
 Day 3−0,087−0,016 to 0,0060,391
 ΔBMI−0,008−0,019 to 0,0180,937
HR
 Day 10,063−0,002 to 0,0040,533
 Day 3−0,078−0,008 to 0,0040,438
 ΔHR0,013−0,001 to 0,0010,899
SBP
 Day 10,102−0,001 to 0,0040,314
 Day 30,098−0,002 to 0,0060,333
 ΔSBP0,2070,000 to 0,0030,039
 Day 10,4810,267 to 0,574<0,0010,4000,185 to 0,513<0,001
 Day 30,4860,218 to 0,464<0,0010,3810,146 to 0,389<0,001
 Δ0,2670,044 to 0,2760,007
 Day 10,131−0,035 to 0,1720,193
 Day 30,2200,012 to 0,2030,0280,088−0,041 to 0,1280,311
 Δ0,099−0,038 to 0,1130,325
 Day 1−0,275−1,231 to −0,2160,0060,165−0,503 to 1,3720,360
 Day 3−0,399−1,232 to −0,455<0,0010,034−0,812 to 0,9570,870
 Δ0,0680,203 to 0,4130,502
 Day 10,3450,500 to 1,704<0,0010,270−0,224 to 1,9510,118
 Day 30,4390,630 to 1,503<0,0010,256−0,393 to 1,6410,226
 Δ−0,040−0,443 to 0,2970,696
pUrea
 Day 10,3090,002 to 0,0090,0020,116−0,002 to 0,0070,342
 Day 30,3820,003 to 0,008<0,0010,121−0,002 to 0,0050,335
 ΔpUrea−0,172−0,003 to 0,0000,087
Albumin at day 1−0,049−0,099 to 0,0600,626
Hemoglobin at day 10,076−0,009 to 0,0210,451

Day 1 values are compared with day 1 hsTnT; day 3 values are compared with day 3 hsTnT; Δ, age, sex, DM, HgBA1c, LVEF, ischemic HF, and medications are compared with changes (Δ) in hsTnT between day 1 and day 3 (day 3–day 1).
DM: diabetes mellitus; HgBA1c: glycated hemoglobin; LVEF: left ventricular ejection fraction; HF: heart failure; ACEi: angiotensin converting enzyme inhibitors; BMI: body mass index; HR: heart rate; SBP: systolic blood pressure; NTproBNP: N-terminal probrain natriuretic peptide; hsTnT: high sensitivity troponin T; eGFR: estimated glomerular filtration rate; pCr: plasma creatinine; pUrea: plasma urea; Δ: changes between day 3 and day 1 (day 3–day 1).