Research Article
Mean Platelet Volume in Patients with Obstructive Sleep Apnea and Its Relationship with Simpler Heart Rate Derivatives
Table 1
Anthropometric, clinical features, and biochemical variables of the two groups.
| Variables | OSA () | Controls () | value |
| Age, years | 48 ± 11 | 44 ± 11 | 0.101a | Male, (%) | 39 (75) | 21 (70) | 0.623c | Body mass index, kg/m2 | 32 (25–47) | 28.5 (20–49) | 0.07b | Fasting glucose, mg/dL | 91 (75–99) | 89 (74–99) | 0.562b | Triglycerides, mg/dL | 126 (45–147) | 124 (57–149) | 0.308b | HDL cholesterol, mg/dL | 41 (27–82) | 45 (28–76) | 0.175b | LDL cholesterol, mg/dL | 119 ± 28 | 116 ± 29 | 0.818a | Creatinine, mg/dL | 0.85 (0.5–1.4) | 0.81 (0.5–1.3) | 0.667b | C-reactive protein, mg/dL | 4.3 (0.3–6.1) | 3.6 (0.1–5.6) | 0.166b | Fibrinogen, mg/dL | 326 ± 71 | 311 ± 62 | 0.424a | Hemoglobin, mg/dL | 14.5 (11–16) | 14.4 (11–16) | 0.606b | RDW | 13.2 (9–19) | 13.6 (12–19) | 0.307b | White blood cells, /mm3 | 6.8 ± 1.6 | 7.2 ± 1.9 | 0.329a | Neutrophil/mm3 | 3.9 (2.4–5.9) | 3.9 (1.3–6.6) | 0.270b | Lymphocyte/mm3 | 2.7 (1.9–6.3) | 2.5 (2.1–4.7) | 0.577b | Neutrophil/lymphocyte | 1.5 (0.5–3.4) | 1.5 (0.5–4.4) | 0.551b | Platelet count (×109/L) | 259 ± 62 | 235 ± 44.7 | 0.07a | Mean platelet volume (fL) | 8.5 ± 1.1 | 8.8 ± 0.8 | 0.09a | Apnea hypopnea index score | 29 (8–75) | 1 (0–4) | <0.001c | SaO2 < 90%, PRTS | 27 ± 12 | 1.2 ± 0.8 | <0.001a | Mild-Moderate OSA, (%) | 28 (53.8) | 0 | <0.001c | Severe OSA, (%) | 24 (46.2) | 0 | <0.001b | Duration of OSA, years | 4 ± 1 | 0 | <0.001a | Minimum HR-PSG | 31 (25–60) | 31 (25–63) | 0.465b | Maximum HR-PSG | 131 (68–150) | 124 (96–148) | 0.832b | Maximum HR-minimum HR PSG | 91 ± 23 | 89 ± 22 | 0.645a | Mean HR-PSG | 67 ± 8 | 69 ± 9 | 0.312a | HRPI-PSG | 1.4 ± 0.4 | 1.3 ± 0.4 | 0.494a | Sleep time, minutes | 392 ± 36 | 385 ± 44 | 0.644a |
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Abbreviations: HDL: high-density lipoprotein; LDL: low-density lipoprotein; RDW: red blood cell distribution width; HR: heart rate (beats/minute), PRTS: percentage of recording time spent; SaO2: arterial oxygen saturation; PSG: polysomnography. aStudent’s -test. bMann-Whitney test. cChi-square test.
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