Table 1: Diagnostic criteria proposed for the clinical diagnosis of the MetS.

Clinical measuresWHO (1998) [5]EGIR (1999) [6]ATPIII (2001) [7]AACE (2003) [8]IDF (2005) [9]

Insulin resistanceIGT, IFG, T2DM, or lowered insulin Sensitivitya
plus any 2 of the following
Plasma insulin >75th percentile
plus any 2 of the following
None,  but any 3 of the following 5  featuresIGT or IFG
plus any of thefollowing based on the clinical judgment

Body weightMen: waist-to-hip ratio >0.90;
women: waist-to-hip ratio >0.85 and/or BMI > 30 kg/m2
WC ≥94 cm in men or ≥80 cm in womenWC ≥102 cm in men or ≥88 cm in womenBMI ≥ 25 kg/m2Increased WC (population specific)
plus any 2 of the following

LipidsTGs ≥150 mg/dL and/or HDL-C
<35 mg/dL in men or <39 mg/dL in women
TGs ≥150 mg/dL and/or HDL-C
<39 mg/dL in men or women
TGs ≥150 mg/dL
HDL-C <40 mg/dL in men or <50 mg/dL in women
TGs ≥150 mg/dL and HDL-C <40 mg/dL in men or <50 mg/dL in womenTGs ≥150 mg/dL or on TGs Rx.
HDL-C <40 mg/dL in men or <50 mg/dL in women or on HDL-C Rx

Blood pressure≥140/90 mm Hg≥140/90 mm Hg or on hypertension Rx≥130/85 mm Hg≥130/85 mm Hg≥130 mm Hg systolic or ≥85 mm Hg diastolic or on hypertension Rx

GlucoseIGT, IFG, or T2DMIGT or IFG (but not diabetes)>110 mg/dL (includes diabetes)IGT or IFG (but not diabetes)≥100 mg/dL (includes diabetes)b

OtherMicroalbuminuria: Urinary excretion rate of >20 mg/min or albumin: creatinine ratio of >30 mg/g. Other features of insulin resistancec

aInsulin sensitivity measured under hyperinsulinemic euglycemic conditions, glucose uptake below lowest quartile for background population under investigation.
bIn 2003, the American Diabetes Association (ADA) changed the criteria for IFG tolerance from >110 mg/dl to >100 mg/dl [10].
cIncludes family history of type 2 diabetes mellitus, polycystic ovary syndrome, sedentary lifestyle, advancing age, and ethnic groups susceptible to type 2 diabetes mellitus.
BMI: body mass index; HDL-C: high density lipoprotein cholesterol; IFG: impaired fasting glucose; IGT: impaired glucose tolerance; Rx: receiving treatment; TGs: triglycerides; T2DM: type 2 diabetes mellitus; WC: waist circumference.