[Retracted] A Comprehensive Review on Metabolic Syndrome

Table 1

Diagnostic criteria proposed for the clinical diagnosis of the MetS.

Clinical measures	WHO (1998) [5]	EGIR (1999) [6]	ATPIII (2001) [7]	AACE (2003) [8]	IDF (2005) [9]
Insulin resistance	IGT, IFG, T2DM, or lowered insulin Sensitivity^a; plus any 2 of the following	Plasma insulin >75th percentile; plus any 2 of the following	None,  but any 3 of the following 5  features	IGT or IFG; plus any of thefollowing based on the clinical judgment	None
Body weight	Men: waist-to-hip ratio >0.90; women: waist-to-hip ratio >0.85 and/or BMI > 30 kg/m^2	WC ≥94 cm in men or ≥80 cm in women	WC ≥102 cm in men or ≥88 cm in women	BMI ≥ 25 kg/m^2	Increased WC (population specific); plus any 2 of the following
Lipids	TGs ≥150 mg/dL and/or HDL-C; <35 mg/dL in men or <39 mg/dL in women	TGs ≥150 mg/dL and/or HDL-C; <39 mg/dL in men or women	TGs ≥150 mg/dL; HDL-C <40 mg/dL in men or <50 mg/dL in women	TGs ≥150 mg/dL and HDL-C <40 mg/dL in men or <50 mg/dL in women	TGs ≥150 mg/dL or on TGs Rx.; HDL-C <40 mg/dL in men or <50 mg/dL in women or on HDL-C Rx
Blood pressure	≥140/90 mm Hg	≥140/90 mm Hg or on hypertension Rx	≥130/85 mm Hg	≥130/85 mm Hg	≥130 mm Hg systolic or ≥85 mm Hg diastolic or on hypertension Rx
Glucose	IGT, IFG, or T2DM	IGT or IFG (but not diabetes)	>110 mg/dL (includes diabetes)	IGT or IFG (but not diabetes)	≥100 mg/dL (includes diabetes)^b
Other	Microalbuminuria: Urinary excretion rate of >20 mg/min or albumin: creatinine ratio of >30 mg/g.			Other features of insulin resistance^c

 ^aInsulin sensitivity measured under hyperinsulinemic euglycemic conditions, glucose uptake below lowest quartile for background population under investigation.
^bIn 2003, the American Diabetes Association (ADA) changed the criteria for IFG tolerance from >110 mg/dl to >100 mg/dl [10].
^cIncludes family history of type 2 diabetes mellitus, polycystic ovary syndrome, sedentary lifestyle, advancing age, and ethnic groups susceptible to type 2 diabetes mellitus.
BMI: body mass index; HDL-C: high density lipoprotein cholesterol; IFG: impaired fasting glucose; IGT: impaired glucose tolerance; Rx: receiving treatment; TGs: triglycerides; T2DM: type 2 diabetes mellitus; WC: waist circumference.